使用植入式迷走神經刺激治療雷葛氏症候群(Lennox-Gastaut syndrome，LGS)病 患(重度痙攣)發現有效,且可恢復低於正常之HRV
Vagus nerve stimulation improves severely impaired heart rate variability in a patient with Lennox-Gastaut-Syndrome.
Seizure. 2008; 17(5):469-72 (ISSN: 1059-1311)
Koenig SA; Longin E; Bell N; Reinhard J; Gerstner T
Children's Hospital, University of Mannheim, Theodor-Kutzer-Ufer, Mannheim, Germany. Drstkoenig@aol.com

Vagus nerve stimulation (VNS) is a new therapeutic option for refractory epilepsy. We report a patient with Lennox-Gastaut-Syndrome (LGS) and a severe impairment of heart rate variability (HRV), we could demonstrate in our patient that HRV was improved by VNS.

Lennox-Gastaut syndrome is a severe form of epilepsy. Seizures usually begin before 4 years of age. 北美的Esai公司宣佈，美國食品藥物管理局(FDA)核准rufinamide (Banzel)作為4歲以上小孩及成人與痙攣相關之雷葛氏症候群(Lennox-Gastaut syndrome，LGS)的輔助治療。